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TCMDC-136364

Chemical Structure : TCMDC-136364

CAS No.: 842148-40-7

TCMDC-136364 (AKT Kinase Inhibitor, GSK Akt inhibitor, TCMDC136364)

Catalog No.: PC-42485Not For Human Use, Lab Use Only.

TCMDC-136364 (AKT Kinase Inhibitor) is an Akt kinase inhibitor, selectively inhibits Akt in proliferating cells expressing Trop-2, also potently inhibits P. falciparum multidrug resistant strain Dd2.

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Biological Activity

TCMDC-136364 (AKT Kinase Inhibitor) is an Akt kinase inhibitor, selectively inhibits Akt in proliferating cells expressing Trop-2, also potently inhibits P. falciparum multidrug resistant strain Dd2.

Physicochemical Properties

M.Wt 357.3672
Formula C16H19N7O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-

References

1. Patent WO2013171777 A2.
2. Francisco-Javier Gamo, et al. Nature. 2010 May 20;465(7296):305-10.

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