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Chemical Structure : TCS 1102
CAS No.: 916141-36-1
Catalog No.: PC-42733Not For Human Use, Lab Use Only.
TCS 1102 is a potent and selective dual Orexin receptor antagonist with Ki of 0.2/3 nM for hOX2R/hOX1R respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $258 | In stock | |
| 100 mg | $448 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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TCS 1102 is a potent and selective dual Orexin receptor antagonist with Ki of 0.2/3 nM for hOX2R/hOX1R respectively.
TCS 1102 demonstrates excellent in vitro cell based activity, brain penetration, and low to moderate bioavailability in rats.
| M.Wt | 470.5859 | |
| Formula | C27H26N4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-Pyrrolidinecarboxamide, N-[1,1'-biphenyl]-2-yl-1-[2-[(1-methyl-1H-benzimidazol-2-yl)thio]acetyl]-, (2S)- |
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1. Bergman JM, et al. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1425-30.
2. Khoo SY, et al. PLoS One. 2017 Mar 15;12(3):e0173967.
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