Chemical Structure : TDI-11861
CAS No.: 2857049-72-8
Catalog No.: PC-49437Not For Human Use, Lab Use Only.
TDI-11861 a potent, selective second-generation soluble adenylyl cyclase (sAC, ADCY10) inhibitor with cellular IC50 of 5.5 nM.
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TDI-11861 a potent, selective second-generation soluble adenylyl cyclase (sAC, ADCY10) inhibitor with cellular IC50 of 5.5 nM.
M.Wt | 494.928 | |
Formula | C22H25ClF2N6O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(R)-(4-(2-(2-((3-(2-amino-6-chloropyrimidin-4-yl)-1-(difluoromethyl)-1H-pyrazol-4-yl)methyl)phenoxy)ethyl)morpholin-3-yl)methanol |
1. Michael Miller, et al. Journal of Medicinal Chemistry, November 8, 2022.
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