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TH-1177

Chemical Structure : TH-1177

CAS No.: 300554-57-8

TH-1177 (TH1177)

Catalog No.: PC-22128Not For Human Use, Lab Use Only.

TH-1177 is a small molecule TRPV6 calcium channel inhibitor, effectively blocks calcium entry in LNCaP prostate cancer cells and demonstrates inhibitory effects on prostate cancer proliferation.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

TH-1177 is a small molecule TRPV6 calcium channel inhibitor, effectively blocks calcium entry in LNCaP prostate cancer cells and demonstrates inhibitory effects on prostate cancer proliferation.

Physicochemical Properties

M.Wt 435.99
Formula C27H30ClNO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2R)-2-(((4-chlorophenyl)(phenyl)methoxy)methyl)-1-(4-methoxyphenethyl)pyrrolidine

References

1. D M Haverstick, et al. Cancer Res. 2000 Feb 15;60(4):1002-8.

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