Chemical Structure : TH-237A
CAS No.: 935467-97-3
Catalog No.: PC-42798Not For Human Use, Lab Use Only.
TH-237A (meso-GS 164) is a brain penetrant neuroprotective agent that protects neurons against β-amyloid (Aβ) induced neurotoxicity.
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TH-237A (meso-GS 164) is a brain penetrant neuroprotective agent that protects neurons against β-amyloid (Aβ) induced neurotoxicity.
TH-237A increases neuronal survival in the presence of the Aβ peptides in rat isolated neuronal culture with EC50 of 5 nM.
M.Wt | 333.3293 | |
Formula | C18H17F2NO3 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 46 mg/mL |
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Chemical Name/SMILES |
1H,3H,5H-Oxazolo[3,4-c]oxazole-7a(7H)-methanol, 3,5-bis(4-fluorophenyl)-, (3R,5S)-rel- |
1. Kelly E. Desino. Improving Blood Brain Barrier Permeation of Small Molecules Exhibiting Chemotherapeutic and Neuroprotective Effects.
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