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Chemical Structure : TH-3021
Catalog No.: PC-72285Not For Human Use, Lab Use Only.
TH-3021 (SN336384) is a potent and specific inhibitor of Aldo-keto reductase 1C3 (AKR1C3) with IC50 of 110 nM in isolated enzyme assays and 18 nM in cellular assays, displays no inhibitory action against AKR1C1/1C2/1C4 (IC50>30 uM).
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TH-3021 (SN336384) is a potent and specific inhibitor of Aldo-keto reductase 1C3 (AKR1C3) with IC50 of 110 nM in isolated enzyme assays and 18 nM in cellular assays, displays no inhibitory action against AKR1C1/1C2/1C4 (IC50>30 uM).
| M.Wt | 309.794 | |
| Formula | C15H20ClN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jack U Flanagan, et al. Bioorg Med Chem. 2014 Feb 1;22(3):967-77.
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