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Chemical Structure : THIQ
CAS No.: 312637-48-2
Catalog No.: PC-70060Not For Human Use, Lab Use Only.
THIQ is a potent and selective melanocortin 4 receptor (MC4R) agonist with EC50 of 2.1 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $158 | In stock | |
| 25 mg | $278 | In stock | |
| 50 mg | $458 | In stock | |
| 100 mg | Get quote |
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THIQ is a potent and selective melanocortin 4 receptor (MC4R) agonist with EC50 of 2.1 nM.
THIQ has high selectivity over other melanocortin receptors (1184-fold vs MC3R, 350-fold vs MC5R).
THIQ enhances intracavernosal pressure and stimulates erectile activity in rats ex copula.
| M.Wt | 589.181 | |
| Formula | C33H41ClN6O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(R)-N-((R)-1-(4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpiperidin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide |
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1. Sebhat IK, et al. J Med Chem. 2002 Oct 10;45(21):4589-93.
2. Martin WJ, et al. Eur J Pharmacol. 2002 Nov 1;454(1):71-9.
3. Molden BM, et al. Mol Endocrinol. 2015 Nov;29(11):1619-33.
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