Chemical Structure : TKK129
Catalog No.: PC-23705Not For Human Use, Lab Use Only.
TKK129 is a 3-hydroxypropanamidine antimalarial inhibitor of IC50 of 2 nM (Pf3D7), shows excellent antiplasmodial in vitro activity against drug-sensitive and -resistant Plasmodium falciparum strains (IC50=6-16 nM).
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TKK129 is a 3-hydroxypropanamidine antimalarial inhibitor of IC50 of 2 nM (Pf3D7), shows excellent antiplasmodial in vitro activity against drug-sensitive and -resistant Plasmodium falciparum strains (IC50=6-16 nM).
M.Wt | 474.43 | |
Formula | C25H19F5N2O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Knaab TC, et al. J Med Chem. 2024 Dec 26. doi: 10.1021/acs.jmedchem.4c01465.
2. Knaab TC, et al. J Med Chem. 2021 Mar 25;64(6):3035-3047.
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