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TLCK

Chemical Structure : TLCK

CAS No.: 4272-74-6

TLCK (Tos-Lys-CH2Cl, N-alpha-Tosyl-L-lysine chloromethyl ketone)

Catalog No.: PC-24925Not For Human Use, Lab Use Only.

TLCK (Tos-Lys-CH2Cl, N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride ) is a specific, irreversible and covalent inhibitor of serine protease trypsin, modifies His-57 and Ser-195 of trypsin-like proteases and blocks the active site.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TLCK (Tos-Lys-CH2Cl, N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride ) is a specific, irreversible and covalent inhibitor of serine protease trypsin, modifies His-57 and Ser-195 of trypsin-like proteases and blocks the active site.

Physicochemical Properties

M.Wt 369.30
Formula C14H22Cl2N2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-(7-amino-1-chloro-2-oxoheptan-3-yl)-4-methylbenzenesulfonamide hydrochloride

References

1. James C Powers, et al. Chem Rev. 2002 Dec;102(12):4639-750.

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