Chemical Structure : TLCK
CAS No.: 4272-74-6
Catalog No.: PC-24925Not For Human Use, Lab Use Only.
TLCK (Tos-Lys-CH2Cl, N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride ) is a specific, irreversible and covalent inhibitor of serine protease trypsin, modifies His-57 and Ser-195 of trypsin-like proteases and blocks the active site.
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TLCK (Tos-Lys-CH2Cl, N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride ) is a specific, irreversible and covalent inhibitor of serine protease trypsin, modifies His-57 and Ser-195 of trypsin-like proteases and blocks the active site.
M.Wt | 369.30 | |
Formula | C14H22Cl2N2O3S | |
Appearance | Solid | |
Storage |
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|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
(S)-N-(7-amino-1-chloro-2-oxoheptan-3-yl)-4-methylbenzenesulfonamide hydrochloride |
1. James C Powers, et al. Chem Rev. 2002 Dec;102(12):4639-750.
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