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Chemical Structure : TLR2 activator R-7d
Catalog No.: PC-22703Not For Human Use, Lab Use Only.
TLR2 activator R-7d is a highly potent and selective human TLR2 activator with EC50 of 116 pM in human THP-1 cells, promotes TLR1/2-induced NF-κB promoter activation.
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TLR2 activator R-7d is a highly potent and selective human TLR2 activator with EC50 of 116 pM in human THP-1 cells, promotes TLR1/2-induced NF-κB promoter activation.
R-7d significantly stimulated the activation of the TLR1/2-induced NF-κB promoter in HEK-293T cells, does not influence the activation of the NF-κB promoter by TLR2/TLR6.
| M.Wt | 616.88 | |
| Formula | C34H64O9 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jia H, et al. J Med Chem. 2024 Jul 12. doi: 10.1021/acs.jmedchem.4c00886.
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