TLR7 agonist 17b

Chemical Structure : TLR7 agonist 17b

Catalog No.: PC-21154Not For Human Use, Lab Use Only.

TLR7 agonist 17b is a potent, selective TLR7 agonist with EC50 of 18 nM in Ramos Blue reporter assays, >500-fold selective for TLR7 over TLR8.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

TLR7 agonist 17b is a potent, selective TLR7 agonist with EC50 of 18 nM in Ramos Blue reporter assays, >500-fold selective for TLR7 over TLR8.
TLR7 agonist 17b 35-fold more potent than R848.
TLR7 agonist 17b potently induces the release of IFNα and TNFα from hPBMCs at low-nanomolar concentrations.

Physicochemical Properties

M.Wt	516.65
Formula	C29H36N6O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	tert-Butyl (3-((4-((4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)methyl)phenyl)amino)-3-oxopropyl)carbamate

References

1. Emma G. DeYoung, et al. ACS Medicinal Chemistry Letters 2023

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

TLR7 agonist 17b

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.