TLX agonist 1 | TLX agonist | Probechem Biochemicals

Chemical Structure : TLX agonist 1

CAS No.: 958323-31-4

TLX agonist 1 (Compound ccrp2)

Catalog No.: PC-27591Not For Human Use, Lab Use Only.

TLX agonist 1 (Compound ccrp2) is a specific small molecule agonist of orphan nuclear receptor tailless (TLX, NR2E1), specifically binds to TLX LBD with Kd of 650 nM, potentiates TLX transcriptional repressive activity.

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Biological Activity

TLX agonist 1 (Compound ccrp2) is a specific small molecule agonist of orphan nuclear receptor tailless (TLX, NR2E1), specifically binds to TLX LBD with Kd of 650 nM, potentiates TLX transcriptional repressive activity.
TLX agonist 1 does not bind two unrelated nuclear receptors ERβ and LXRβ.

Physicochemical Properties

M.Wt	374.49
Formula	C23H26N4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4-Benzhydrylpiperazin-1-yl)(1,5-dimethyl-1H-pyrazol-3-yl)methanone

References

1. Benod C, et al. PLoS One. 2014 Jun 17;9(6):e99440.

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TLX agonist 1 (Compound ccrp2)

Biological Activity

Physicochemical Properties

References

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