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TMX-4102

Chemical Structure : TMX-4102

CAS No.:

TMX-4102 (TMX4102)

Catalog No.: PC-20165Not For Human Use, Lab Use Only.

TMX-4102 (TMX4102) is a highly potent, selective PIP4K2C binder with KD of 0.45 nM, shows no affinity for PIP4K2B and PIP4K2A (KD>10 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    TMX-4102 (TMX4102) is a highly potent, selective PIP4K2C binder with KD of 0.45 nM, shows no affinity for PIP4K2B and PIP4K2A (KD>10 uM).
    TMX-4102 exhibited selectivity for PIP4K2C over other lipid kinase isoforms and the non-lipid kinases in the KINOMEscan.

    Physicochemical Properties

    M.Wt 469.93
    Formula C26H20ClN5O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-2-((4-([1,1'-biphenyl]-3-yl)-5-chloropyrimidin-2-yl)amino)-6,6a,7,8-tetrahydro-9H-pyrido[2,3-b]pyrrolo[1,2-d][1,4]oxazin-9-one

    References

    1. Teng M, et al. Angew Chem Int Ed Engl. 2023 Mar 10:e202302364.

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