TMX-4102 | PIP4K2C binder | Probechem Biochemicals

Chemical Structure : TMX-4102

TMX-4102 (TMX4102)

Catalog No.: PC-20165Not For Human Use, Lab Use Only.

TMX-4102 (TMX4102) is a highly potent, selective PIP4K2C binder with KD of 0.45 nM, shows no affinity for PIP4K2B and PIP4K2A (KD>10 uM).

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Biological Activity

TMX-4102 (TMX4102) is a highly potent, selective PIP4K2C binder with KD of 0.45 nM, shows no affinity for PIP4K2B and PIP4K2A (KD>10 uM).
TMX-4102 exhibited selectivity for PIP4K2C over other lipid kinase isoforms and the non-lipid kinases in the KINOMEscan.

Physicochemical Properties

M.Wt	469.93
Formula	C26H20ClN5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-((4-([1,1'-biphenyl]-3-yl)-5-chloropyrimidin-2-yl)amino)-6,6a,7,8-tetrahydro-9H-pyrido[2,3-b]pyrrolo[1,2-d][1,4]oxazin-9-one

References

1. Teng M, et al. Angew Chem Int Ed Engl. 2023 Mar 10:e202302364.

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TMX-4102 (TMX4102)

Biological Activity

Physicochemical Properties

References

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