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TNG-2673

Chemical Structure : TNG-2673

CAS No.:

TNG-2673 (TNG2673)

Catalog No.: PC-28132Not For Human Use, Lab Use Only.

TNG-2673 is a potent, selective, allosteric inhibitor of Golgi glycosyltransferase MGAT1 with IC50 of 43 nM, inhibits MGAT1 through a UDP-noncompetitive mechanism.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

TNG-2673 is a potent, selective, allosteric inhibitor of Golgi glycosyltransferase MGAT1 with IC50 of 43 nM, inhibits MGAT1 through a UDP-noncompetitive mechanism.

Physicochemical Properties

M.Wt 478.50
Formula C25H24F2N6O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(3-(aminomethyl)-5-(3,5-dimethyl-4H-1,2,4-triazol-4-yl)phenyl)-2-cyclobutoxy-7,8-difluoroquinoline-4-carboxamide

References

1. Vassallo KM, et al. J Biol Chem. 2026 Sep 12:113551.

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