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TRAP-6

Chemical Structure : TRAP-6

CAS No.: 141136-83-6

TRAP-6 (Thrombin Receptor Activator Peptide 6)

Catalog No.: PC-47484Not For Human Use, Lab Use Only.

A PAR1 peptide fragment (residues 42-47) that acts as a PAR1 agonist.

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Biological Activity

A PAR1 peptide fragment (residues 42-47) that acts as a PAR1 agonist; stimulates platelet aggregation (EC50=0.8 uM), promotes intracellular Ca2+ mobilization and induces rapid phosphodiesterase 3A (PDE3A) phosphorylation in vitro.

Physicochemical Properties

M.Wt 748.8701
Formula C34H56N10O9
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 28 mg/mL

Chemical Name/SMILES

L-Asparagine, L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-

References

1. Vassallo RR Jr, et al. J Biol Chem. 1992 Mar 25;267(9):6081-5.

2. Kaufmann R, et al. J Neurooncol. 1999 Apr;42(2):131-6.

3. Hunter RW, et al. J Biol Chem. 2009 May 1;284(18):12339-48.

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