TRF1-TIN2 interaction inhibitor 1

Chemical Structure : TRF1-TIN2 interaction inhibitor 1

Catalog No.: PC-25765Not For Human Use, Lab Use Only.

TRF1-TIN2 interaction inhibitor 1 (Compound 40) is a first-in-class inhibitor of the TRF1:TIN2 interaction with IC50 of 67 uM, binds to TRFH domain of TRF1 (TRF1 TRFH) with KD of 29 uM, disrupts shelterin complex assembly.

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Biological Activity

Physicochemical Properties

M.Wt	374.41
Formula	C19H18O6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((3,5-dimethoxybenzyl)oxy)naphthalene-1-sulfonic acid

References

1. Casale G, et al. Sci Rep. 2025 Nov 20;15(1):40922.

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TRF1-TIN2 interaction inhibitor 1

Biological Activity

Physicochemical Properties

References

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