TRPM2 inhibitor LC4 | TRPM2 inhibitor | Probechem Biochemicals

Chemical Structure : TRPM2-IN-LC4

TRPM2-IN-LC4 (TRPM2 inhibitor LC4)

Catalog No.: PC-25552Not For Human Use, Lab Use Only.

TRPM2 inhibitor LC4 is a potent and selective TRPM2 inhibitor with IC50 of 0.66 uM.

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Biological Activity

TRPM2 inhibitor LC4 is a potent and selective TRPM2 inhibitor with IC50 of 0.66 uM.
TRPM2 inhibitor LC4 reduces the infarct volume and oxidative-stress level in transient middle cerebral artery occlusion (tMCAO) model.

Physicochemical Properties

M.Wt	390.53
Formula	C25H30N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((3s,5s,7s)-adamantan-1-yl)-6-(pyrrolidine-1-carbonyl)-3aH-indene-4-carboxamide

References

1. Lu T, et al. Eur J Med Chem. 2025 Sep 13;300:118172.

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TRPM2-IN-LC4 (TRPM2 inhibitor LC4)

Biological Activity

Physicochemical Properties

References

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