Catalog No.: PC-35234Not For Human Use, Lab Use Only.
TRPM4 inhibitor 5 (TMEM206 inhibitor CBA) is a potent and selective inhibitor of TRPM4 with IC50 of 1.5 uM (Na+ influx), also inhibits TMEM206 with IC50 of 9.55 uM.
TRPM4 inhibitor 5 (TMEM206 inhibitor CBA) is a potent and selective inhibitor of TRPM4 with IC50 of 1.5 uM (Na+ influx), also inhibits TMEM206 with IC50 of 9.55 uM.
TRPM4 inhibitor 5 (TMEM206 inhibitor CBA) selectively inhibits TRPM4 overexpressed in HEK293 cells (IC50=1.8 uM) using classical patch-clamp electrophysiology recordings, shows no significant effect on the TRPM5 current, as well as other TRP family members including TRPM7, TRPM8, TRPV1 and TRPV6.
TRPM4 inhibitor 5 (TMEM206 inhibitor CBA)demonstrates effective and specific inhibition of TMEM206.
