TTBK1-IN-2

Chemical Structure : TTBK1-IN-2

CAS No.: 2765453-51-6

Catalog No.: PC-26744Not For Human Use, Lab Use Only.

TTBK1-IN-2 (Compound 29) is a potent, brain penetrant Tau-Tubulin kinase (TTBK1) inhibitor with IC50 of 0.24 uM, reduces TDP-43 phosphorylation both in vitro and in vivo.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$328	In stock
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Biological Activity

TTBK1-IN-2 (Compound 29) is a potent, brain penetrant Tau-Tubulin kinase (TTBK1) inhibitor with IC50 of 0.24 uM, reduces TDP-43 phosphorylation both in vitro and in vivo.

Physicochemical Properties

M.Wt	336.78
Formula	C18H13ClN4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(4-Chlorophenoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

References

1. Nozal V, et al. J Med Chem. 2022;65(2):1585-1607.

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TTBK1-IN-2

Biological Activity

Physicochemical Properties

References

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