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TTBK1/2-IN-1

Chemical Structure : TTBK1/2-IN-1

CAS No.: 2342571-09-7

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TTBK1/2-IN-1

Catalog No.: PC-26745Not For Human Use, Lab Use Only.

TTBK1/2-IN-1 (Compound 3) is a potent tau tubulin kinase 1 and 2 (TTBK1 and TTBK2) inhibitor with IC50 of 816 nM and 384 nM nM for TTBK1 and TTBK2, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

TTBK1/2-IN-1 (Compound 3) is a potent tau tubulin kinase 1 and 2 (TTBK1 and TTBK2) inhibitor with IC50 of 816 nM and 384 nM nM for TTBK1 and TTBK2, respectively.

Physicochemical Properties

M.Wt 292.34
Formula C17H16N4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-Butyn-2-ol, 4-[3-(2-amino-4-pyrimidinyl)-1H-indol-5-yl]-2-methyl-

References

1. Bashore FM, et al. Sci Rep. 2023 Apr 14;13(1):6118.

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