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Chemical Structure : TTFB
CAS No.: 352560-76-0
Catalog No.: PC-72756Not For Human Use, Lab Use Only.
TTFB (ZAC antagonist TTFB) is a selective antagonist (negative allosteric modulator) of Zinc-Activated Channel (ZAC) with IC50 of 3 uM.
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|---|---|---|---|
| 10 mg | $228 | In stock | |
| 50 mg | $628 | In stock | |
| 100 mg | $1080 | In stock | |
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TTFB (ZAC antagonist TTFB) is a selective antagonist (negative allosteric modulator) of Zinc-Activated Channel (ZAC) with IC50 of 3 uM.
TTFB dispalys no significant agonist, antagonist or modulatory activity on a panel of four classical CLR subfamilies: the m5-HT3AR, the hα3β4 nAChR, the hα1β2γ2S GABAAR and the hα1 GlyR.
TTFB mediates equipotent and voltage-independent inhibition of agonist-evoked and spontaneous ZAC signaling.
| M.Wt | 278.345 | |
| Formula | C14H15FN2OS | |
| Appearance | Solid | |
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1. Nawid Madjroh, et al. Biochem Pharmacol. 2021 Nov;193:114782.
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