TYK2-JH1 inhibitor 30

Chemical Structure : TYK2-JH1 inhibitor 30

CAS No.: 2244061-66-1

Catalog No.: PC-49112Not For Human Use, Lab Use Only.

TYK2-JH1 inhibitor 30 is a potent and selective TYK2-JH1 inhibitor with Ki of 0.51 nM.

Packing	Price	Stock
5 mg	$248	In stock
10 mg	$398	In stock
25 mg	$598	In stock
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Biological Activity

TYK2-JH1 inhibitor 30 is a potent and selective TYK2-JH1 inhibitor with Ki of 0.51 nM.
TYK2-JH1 inhibitor 30 shows excellent selectivity, pharmacokinetic properties, and in vivo efficacy in a mouse psoriasis model.

Physicochemical Properties

M.Wt	434.447
Formula	C24H20F2N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2,6-difluorophenyl)-4-((4-(pyrrolidine-1-carbonyl)phenyl)amino)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one

References

1. Silvana Leit, et al. Bioorg Med Chem Lett. 2022 Jul 13;73:128891.

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