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Tafenoquine

Chemical Structure : Tafenoquine

CAS No.: 106635-80-7

Tafenoquine (SB-252263;Tafenoquine;WR 238605)

Catalog No.: PC-63381Not For Human Use, Lab Use Only.

Tafenoquine (SB-252263, Tafenoquine, WR 238605) is a long-acting, orally active anti-malarial agent to prevent malaria that is holoendemic for Plasmodium falciparum..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Tafenoquine (SB-252263, Tafenoquine, WR 238605) is a long-acting, orally active anti-malarial agent to prevent malaria that is holoendemic for Plasmodium falciparum.

Parasite Infection

Phase 3 Clinical

Physicochemical Properties

M.Wt 463.501
Formula C24H28F3N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N4-(2,6-dimethoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinolin-8-yl)pentane-1,4-diamine

References

1. Shanks GD, et al. Clin Infect Dis. 2001 Dec 15;33(12):1968-74.

2. Ramharter M, et al. Am J Trop Med Hyg. 2002 Jul;67(1):39-43.

3. Pradines B, et al. Antimicrob Agents Chemother. 2006 Sep;50(9):3225-6.

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