Tamoxifen | SERM | Probechem Biochemicals

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Chemical Structure : Tamoxifen

CAS No.: 10540-29-1

Tamoxifen (ICI 47699, (Z)-Tamoxifen, Trans-tamoxifen)

Catalog No.: PC-28232Not For Human Use, Lab Use Only.

Tamoxifen (ICI 47699) is a nonsteroidal antiestrogen and orally active, selective estrogen receptor modulator (SERM), targets estrogen binding to ER, also inhibits the activity of PKC and inhibits cancer cell proliferation, is used mainly for the treatment of breast cancer.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	371.52
Formula	C26H29NO
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-

References

1. Osborne CK. N Engl J Med. 1998 Nov 26;339(22):1609-18.

2. Hawariah A, et al Anticancer Res. 1998 Nov-Dec;18(6A):4383-6.

3. Huet S, et al. Eur J Cancer. 1993;29A(10):1377-83.

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Tamoxifen (ICI 47699, (Z)-Tamoxifen, Trans-tamoxifen)

Biological Activity

Physicochemical Properties

References

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