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Chemical Structure : Telratolimod
CAS No.: 1359993-59-1
Catalog No.: PC-61400Not For Human Use, Lab Use Only.
Telratolimod (MEDI 9197, 3M 052) is a novel, injectable, tissue-retained TLR7/8 agonist that forms a tissue depot with gradual, sustained release, allowing local TLR triggering activity without systemic cytokine release.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $388 | In stock | |
| 10 mg | $558 | In stock | |
| 25 mg | $898 | In stock | |
| 100 mg | Get quote | ||
| 1 g | Get quote |
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Telratolimod (MEDI 9197, 3M 052) is a novel, injectable, tissue-retained TLR7/8 agonist that forms a tissue depot with gradual, sustained release, allowing local TLR triggering activity without systemic cytokine release.
Telratolimod (MEDI 9197, 3M 052) induces local innate immune activation as well as systemic, antigen-specific CD8+ T cell responses which suppressed distant, uninjected tumors; is currently under clinical development for use in vaccines and cancer therapy.
| M.Wt | 593.901 | |
| Formula | C36H59N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-{4-[(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy]butyl}octadecanamide |
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1. Singh M, et al. J Immunol. 2014 Nov 1;193(9):4722-31.
2. Van Hoeven N, et al. Sci Rep. 2017 Apr 21;7:46426.
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