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Thalidomide-4-OH

Chemical Structure : Thalidomide-4-OH

CAS No.: 5054-59-1

Thalidomide-4-OH (E3 Ligase Ligand 2, Cereblon ligand 2)

Catalog No.: PC-60101Not For Human Use, Lab Use Only.

Thalidomide-4-OH (Cereblon ligand 2) is a Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein for PROTAC design.

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Biological Activity

Thalidomide-4-OH (Cereblon ligand 2) is a Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein for PROTAC design.

Physicochemical Properties

M.Wt 274.232
Formula C13H10N2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione

References

1. Robb CM, et al. Chem Commun (Camb). 2017 Jul 4;53(54):7577-7580.

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