Thalidomide-O-COOH |CAS:1061605-21-7 Probechem Biochemicals

Chemical Structure : Thalidomide-O-COOH

CAS No.: 1061605-21-7

Catalog No.: PC-60108Not For Human Use, Lab Use Only.

Thalidomide-O-COOH (Cereblon ligand 3) is a Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein for PROTAC design.

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Biological Activity

Thalidomide-O-COOH (Cereblon ligand 3) is a Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein for PROTAC design.

M.Wt	332.268
Formula	C15H12N2O7
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid

1. Lohbeck J, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262.