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Them1 inhibitor Compound U11

Chemical Structure : Them1 inhibitor Compound U11

CAS No.: 2980621-54-1

Them1 inhibitor Compound U11

Catalog No.: PC-25886Not For Human Use, Lab Use Only.

Them1 inhibitor Compound U11 is a small molecule inhibitor of thioesterase superfamily member 1 (Them1) with IC50 of 3.63 uM, selectively inhibits Them1 by binding the START domain (Kd=0.67 uM).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Them1 inhibitor Compound U11 is a small molecule inhibitor of thioesterase superfamily member 1 (Them1) with IC50 of 3.63 uM, selectively inhibits Them1 by binding the START domain (Kd=0.67 uM).

Physicochemical Properties

M.Wt 381.54
Formula C22H27N3OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-methyl-1-(4-((2-methyl-1H-indol-3-yl)(thiophen-2-yl)methyl)piperazin-1-yl)propan-1-one

References

1. Krumm CS, et al. Mol Metab. 2023 Dec;78:101832.

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