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Thienopyridone

Chemical Structure : Thienopyridone

CAS No.: 1018454-97-1

Thienopyridone

Catalog No.: PC-22856Not For Human Use, Lab Use Only.

Thienopyridone is a potent and selective phosphatase of regenerating liver (PRL) phosphatases inhibitor with IC50s of 173 nM, 277 nM and 128 nM for PRL-1 (PTP4A1), PRL-2 (PTP4A2), and PRL-3 (PTP4A3), respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Thienopyridone is a potent and selective phosphatase of regenerating liver (PRL) phosphatases inhibitor with IC50s of 173 nM, 277 nM and 128 nM for PRL-1 (PTP4A1), PRL-2 (PTP4A2), and PRL-3 (PTP4A3), respectively.

Physicochemical Properties

M.Wt 242.30
Formula C13H10N2OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-Amino-2-phenylthieno[3,2-c]pyridin-4(5H)-one

References

1. Daouti S, et al. Cancer Res. 2008 Feb 15;68(4):1162-9.

2. Kostantin E, et al. J Biol Chem. 2016 May 13;291(20):10716-25.

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