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Thonzonium bromide

Chemical Structure : Thonzonium bromide

CAS No.: 553-08-2

Thonzonium bromide

Catalog No.: PC-22873Not For Human Use, Lab Use Only.

Thonzonium bromide is an antibacterial agent, inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo, also is a ATPase p97-Npl4 interaction, boosts antitumor immunity without affecting peripheral Treg cell homeostasis.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Thonzonium bromide is an antibacterial agent, inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo, also is a ATPase p97-Npl4 interaction, boosts antitumor immunity without affecting peripheral Treg cell homeostasis.

Physicochemical Properties

M.Wt 591.72
Formula C32H55BrN4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-((4-Methoxybenzyl)(pyrimidin-2-yl)amino)ethyl)-N,N-dimethylhexadecan-1-aminium bromide

References

1. Zhu X, et al. Biochem Pharmacol. 2016;104:118-130.

2. Nie P, et al. Nat Immunol. 2024 Aug 6. doi: 10.1038/s41590-024-01912-y.

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