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Thymalfasin

Chemical Structure : Thymalfasin

CAS No.: 62304-98-7

Thymalfasin (Thymosin α1)

Catalog No.: PC-47494Not For Human Use, Lab Use Only.

An immunoactive peptide that has been shown to inhibit cell proliferation and induce apoptosis in human leukemia, non-small cell lung cancer, melanoma, and other human cancers.

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1 mg $128 In stock
5 mg $392 In stock
10 mg $688 In stock

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

An immunoactive peptide that has been shown to inhibit cell proliferation and induce apoptosis in human leukemia, non-small cell lung cancer, melanoma, and other human cancers; inhibits the activation of the PI3K/Akt/mTOR signaling pathway, enhances PTEN expression, and shows growth inhibition of breast cancer cells; also exhibited a direct antiviral mechanism of action for HBV and HCV.

Skin Cancer

Approved

Physicochemical Properties

M.Wt 3108.275
Formula C129H215N33O55
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

H2O

Chemical Name/SMILES

L-Asparagine, N-acetyl-L-seryl-L-α-aspartyl-L-alanyl-L-alanyl-L-valyl-L-α-aspartyl-L-threonyl-L-seryl-L-seryl-L-α-glutamyl-L-isoleucyl-L-threonyl-L-threonyl-L-lysyl-L-α-aspartyl-L-leucyl-L-lysyl-L-α-glutamyl-L-lysyl-L-lysyl-L-α-glutamyl-L-valyl-L-valyl-L-

References

1. He C, et al. Medicine (Baltimore). 2017 Apr;96(16):e6606.

2. King RS, et al. Expert Opin Biol Ther. 2015;15 Suppl 1:S41-9.

3. Guo Y, et al. Apoptosis. 2015 Aug;20(8):1109-21.

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