Chemical Structure : Tivozanib
CAS No.:
475108-18-0
Tivozanib
(AV-951, AV951, KRN951)
Catalog No. : PC-42759Not For Human Use, Lab Use Only.
Tivozanib (AV951) is a highly potent inhibitor of pan-VEGFR with IC50s of 60/6.5/15 nM for VEGFR1/2/3.
Packing Price Stock Quantity 5 mg (Free Sample) $28 In stock 0 1 2 3 4 5 10 mg $78 In stock 0 1 2 3 4 5 25 mg $138 In stock 0 1 2 3 4 5 50 mg $248 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4275901
Biological Activity
Tivozanib (AV951) is a highly potent inhibitor of pan-VEGFR with IC50s of 60/6.5/15 nM for VEGFR1/2/3.
Physicochemical Properties
M.Wt
454.8631
Formula
C22H19ClN4O5
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Urea, N-[2-chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)-
References
1. Nakamura K, et al. Cancer Res.
2. Eskens FA, et al. Clin Cancer Res.
3. Momeny M, et al. Sci Rep.
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