Tolrestat | Aldose reductase inhibitor

Chemical Structure : Tolrestat

CAS No.: 82964-04-3

Catalog No.: PC-25937Not For Human Use, Lab Use Only.

Tolrestat (AY-27773) is a potent, orally active aldose reductase inhibitor with IC50 of 35 nM.

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Biological Activity

Tolrestat (AY-27773) is a potent, orally active aldose reductase inhibitor with IC50 of 35 nM.

M.Wt	357.35
Formula	C16H14F3NO3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(6-Methoxy-5-(trifluoromethyl)naphthalene-1-carbonothioyl)-N-methylglycine

1. Sestanj K, et al. J Med Chem. 1984 Mar;27(3):255-6.

2. Srivastava S, et al. 2009 Oct 9;105(8):793-802.