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Chemical Structure : Tpm1.8/9-1
Catalog No.: PC-21809Not For Human Use, Lab Use Only.
Tpm1.8/9-1 (CID 6494468) is a specific small molecule inhibitor of Tpm1.8/9, antagonizes Tpm1.8/9's effects on EMT, Wnt signaling, and resistance to chemotherapy.
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Tpm1.8/9-1 (CID 6494468) is a specific small molecule inhibitor of Tpm1.8/9, antagonizes Tpm1.8/9's effects on EMT, Wnt signaling, and resistance to chemotherapy.
Tpm1.8/9-1 does not affect Tpm1.6/7 or Tpm1.8/9 expression at either the RNA or protein level.
Tpm1.8/9-1 dramatically reduced Wnt/β-catenin signaling.
| M.Wt | 188.27 | |
| Formula | C12H16N2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Tong Xu, et al. Cell Death Differ. 2024 Feb 16. doi: 10.1038/s41418-024-01267-9.
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