Tpm1.8/9-1 | Tpm1.8/9 inhibitor | Probechem Biochemicals

Chemical Structure : Tpm1.8/9-1

Tpm1.8/9-1 (Tpm1.8/9 inhibitor 1, PubChem CID 6494468)

Catalog No.: PC-21809Not For Human Use, Lab Use Only.

Tpm1.8/9-1 (CID 6494468) is a specific small molecule inhibitor of Tpm1.8/9, antagonizes Tpm1.8/9's effects on EMT, Wnt signaling, and resistance to chemotherapy.

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Biological Activity

Tpm1.8/9-1 (CID 6494468) is a specific small molecule inhibitor of Tpm1.8/9, antagonizes Tpm1.8/9's effects on EMT, Wnt signaling, and resistance to chemotherapy.
Tpm1.8/9-1 does not affect Tpm1.6/7 or Tpm1.8/9 expression at either the RNA or protein level.
Tpm1.8/9-1 dramatically reduced Wnt/β-catenin signaling.

Physicochemical Properties

M.Wt	188.27
Formula	C12H16N2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(2-Methyl-indol-1-yl)-propylamine

References

1. Tong Xu, et al. Cell Death Differ. 2024 Feb 16. doi: 10.1038/s41418-024-01267-9.

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Tpm1.8/9-1 (Tpm1.8/9 inhibitor 1, PubChem CID 6494468)

Biological Activity

Physicochemical Properties

References

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