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Trans-ACPD

Chemical Structure : Trans-ACPD

CAS No.: 67684-64-4

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Trans-ACPD (Trans-(±)-ACPD)

Catalog No.: PC-45635Not For Human Use, Lab Use Only.

Trans-ACPD is a equimolecular mixture of (1S,3R)- and (1R,3S)-ACPD, selective agonist for metabotropic glutamate receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Trans-ACPD is a equimolecular mixture of (1S,3R)- and (1R,3S)-ACPD, selective agonist for metabotropic glutamate receptors.
Trans-ACPD is active at both group I and group II mGlu receptors (EC50 values are 2, 15, 23 and ~800 uM at mGluR2, mGluR1, mGluR5 and mGluR4 respectively).

Physicochemical Properties

M.Wt 173.1665
Formula C7H11NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

H2O: 6.2 mg/mL (Need ultrasonic)
Chemical Name/SMILES

1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1R,3S)-rel-

References

1. Conti P,et al. Farmaco. 2002 Nov;57(11):889-95.

2. Knopfel T, et al. J Med Chem. 1995 Apr 28;38(9):1417-26.

3. Klette KL, et al. Brain Res. 1997 May 9;756(1-2):231-40.

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