Chemical Structure : Traxoprodil
Catalog No.: PC-70017Not For Human Use, Lab Use Only.
A potent and NR2B-selective NMDA receptor antagonist.
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A potent and NR2B-selective NMDA receptor antagonist; potently protects cultured hippocampal neurons from glutamate toxicity (IC50=10 nM); shows neuroprotective, analgesic, and anti-Parkinsonian effects in animal studies.
Parkinson's Disease
Phase 2 Discontinued
M.Wt | 327.424 | |
Formula | C20H25NO3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Brimecombe JC, et al. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):11019-24.
2. Chenard BL, et al. J Med Chem. 1995 Aug 4;38(16):3138-45.
3. Steece-Collier K, et al. Exp Neurol. 2000 May;163(1):239-43.
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