Catalog No.: PC-61514Not For Human Use, Lab Use Only.
Traxoprodil (CP101606) is a potent, selective N-methyl-D-aspartate (NMDA) antagonist with selectivity for the NR2B subunit, potently protects cultured hippocampal neurons from glutamate toxicity (IC50=10 nM).
Traxoprodil (CP101606) is a potent, selective N-methyl-D-aspartate (NMDA) antagonist with selectivity for the NR2B subunit, potently protects cultured hippocampal neurons from glutamate toxicity (IC50=10 nM).
Traxoprodil (CP101606) dramatically reduces both the open dwell-time and frequency of channel opening of NR1/NR2B-containing receptors, but only modestly inhibits NR1/NR2A and NR1/NR2C channel activity.
Traxoprodil (CP101606) exhibits neuroprotective, analgesic, and anti-Parkinsonian effects in animal studies.
