Trifarotene |CAS:895542-09-3 Probechem Biochemicals

Chemical Structure : Trifarotene

CAS No.: 895542-09-3

Trifarotene (CD5789;CD-5789)

Catalog No.: PC-35171Not For Human Use, Lab Use Only.

Trifarotene (CD5789, CD-5789) is a potent and selective RARγ agonist with EC50 of 7.7 nM, 500- and 125-fold selectivity over RARα and RARβ.

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Biological Activity

Trifarotene (CD5789, CD-5789) is a potent and selective RARγ agonist with EC50 of 7.7 nM, 500- and 125-fold selectivity over RARα and RARβ.
Trifarotene (CD5789, CD-5789) demonstrates potential for the treatment of acne in clinical trials.

Physicochemical Properties

M.Wt	459.586
Formula	C29H33NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3''-(tert-butyl)-4'-(2-hydroxyethoxy)-4''-(pyrrolidin-1-yl)-[1,1':3',1''-terphenyl]-4-carboxylic acid

References

1. Thoreau E, et al. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1736-1741.

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Trifarotene (CD5789;CD-5789)

Biological Activity

Physicochemical Properties

References

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