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You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-GABA Receptor-U-93631
U-93631

Chemical Structure : U-93631

CAS No.: 152273-12-6

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U-93631 (U93631;U 93631)

Catalog No.: PC-42225Not For Human Use, Lab Use Only.

A potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction; induce a rapid, time-dependent decay of GABA-induced whole-cell Cl- currents in recombinant GABAA receptors.

Physicochemical Properties

M.Wt 299.3676
Formula C17H21N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
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Solubility

DMSO: ≥ 34 mg/mL
Chemical Name/SMILES

Imidazo[1,5-a]quinoxaline-3-carboxylic acid, 4,5-dihydro-4,4-dimethyl-, 1,1-dimethylethyl ester

References

1. Dillon GH, et al. Mol Pharmacol. 1993 Oct;44(4):860-5.

2. Dillon GH, et al. J Pharmacol Exp Ther. 1995 Feb;272(2):597-603.

3. Dillon GH, et al. Br J Pharmacol. 1995 Jun;115(3):539-45.

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