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U 74389G maleate

Chemical Structure : U 74389G maleate

CAS No.: 153190-29-5

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U 74389G maleate (U 74389G)

Catalog No.: PC-70095Not For Human Use, Lab Use Only.

A potent lipid peroxidation inhibitor that has antishock and endothelial protective actions.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent lipid peroxidation inhibitor that has antishock and endothelial protective actions; protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.

Physicochemical Properties

M.Wt 726.9
Formula C37H50N6O2 • C4H4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(8S,10S,13S,14S,17S)-17-(2-(4-(2,6-di(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)acetyl)-10,13-dimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one compound with 1-(1l3-but-2-yn-1-yl)-4l1-tetraoxidane (1:1)

References

1. Farbiszewski R, et al. Eur J Pharmacol. 1994 Apr 4;270(2-3):263-5.

2. Squadrito F, et al. Br J Pharmacol. 1995 Jun;115(3):395-400.

3. Perna AM, et al. Pharmacol Res. 1996 Jul-Aug;34(1-2):25-31.

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