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Chemical Structure : UAMC-1110
CAS No.: 1448440-52-5
Catalog No.: PC-36075Not For Human Use, Lab Use Only.
UAMC-1110 (SP-13786) is a potent, selective small molecule inhibitor of fibroblast activation protein (FAP) with IC50 of 3.2 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $348 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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UAMC-1110 (SP-13786) is a potent, selective small molecule inhibitor of fibroblast activation protein (FAP) with IC50 of 3.2 nM.
UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with IC50 of 1.8 uM.
| M.Wt | 344.322 | |
| Formula | C17H14F2N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide |
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1. Gunderson AJ, et al. PLoS One. 2019 Feb 6;14(2):e0211117.
2. Jansen K, et al. ACS Med Chem Lett. 2013 Mar 18;4(5):491-6.
3. Jansen K, et al. J Med Chem. 2014 Apr 10;57(7):3053-74.
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