UCB1244283 | SV2A modulator | Probechem Biochemicals

Chemical Structure : UCB1244283

UCB1244283 (UCB-1244283)

Catalog No.: PC-25443Not For Human Use, Lab Use Only.

UCB1244283 is a selective allosteric modulator of synaptic vesicle protein 2A (SV2A), selective over SV2B and SV2C, enhances brivaracetam (BRV) binding by occupying an allosteric site near the primary binding site, preventing BRV dissociation.

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Biological Activity

UCB1244283 is a selective allosteric modulator of synaptic vesicle protein 2A (SV2A), selective over SV2B and SV2C, enhances brivaracetam (BRV) binding by occupying an allosteric site near the primary binding site, preventing BRV dissociation.

Physicochemical Properties

M.Wt	311.43
Formula	C20H25NO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(3,5-dimethylphenyl)-N-(2-methoxyphenyl)-3-methylbutanamide

References

1. Mittal A, et al. Proc Natl Acad Sci U S A. 2025 Sep 9;122(36):e2510239122.

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UCB1244283 (UCB-1244283)

Biological Activity

Physicochemical Properties

References

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