UDM-001651 | PAR4 inhibitor | Probechem Biochemicals

Chemical Structure : UDM-001651

UDM-001651 (UDM001651, UDM 001651)

Catalog No.: PC-73008Not For Human Use, Lab Use Only.

UDM-001651 (UDM001651) is a potent, selective, and orally bioavailable PAR4 antagonist with IC50 of 2.4 nM.

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Biological Activity

UDM-001651 (UDM001651) is a potent, selective, and orally bioavailable PAR4 antagonist with IC50 of 2.4 nM.
UDM-001651 demonstrated robust antithrombotic efficacy and no prolongation of kidney bleeding time in a monkey thrombosis model.

Physicochemical Properties

M.Wt	513.56
Formula	C28H23N3O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(4-((3-(Benzyloxy)benzyl)oxy)-6-methoxybenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

References

1. Miller MM, et al. J Med Chem. 2019 Jun 27. J Med Chem. 2019 Aug 22;62(16):7400-7416.

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UDM-001651 (UDM001651, UDM 001651)

Biological Activity

Physicochemical Properties

References

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