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UDM-001651

Chemical Structure : UDM-001651

CAS No.: 1477497-01-0

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UDM-001651 (UDM001651, UDM 001651)

Catalog No.: PC-73008Not For Human Use, Lab Use Only.

UDM-001651 (UDM001651) is a potent, selective, and orally bioavailable PAR4 antagonist with IC50 of 2.4 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    UDM-001651 (UDM001651) is a potent, selective, and orally bioavailable PAR4 antagonist with IC50 of 2.4 nM.
    UDM-001651 demonstrated robust antithrombotic efficacy and no prolongation of kidney bleeding time in a monkey thrombosis model.

    Physicochemical Properties

    M.Wt 513.56
    Formula C28H23N3O5S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    6-(4-((3-(Benzyloxy)benzyl)oxy)-6-methoxybenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

    References

    1. Miller MM, et al. J Med Chem. 2019 Jun 27. J Med Chem. 2019 Aug 22;62(16):7400-7416.

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