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UM-1098

Chemical Structure : UM-1098

CAS No.: 3118718-78-5

UM-1098 (UM1098)

Catalog No.: PC-27718Not For Human Use, Lab Use Only.

UM-1098 is a synthetic macrophage-Inducible C-type Lectin (Mincle) agonist, induces Th17, Th1, Th2 polarizing innate cytokines in mouse PBMCs, induces strong Th1 and Th17 immunity after vaccination with Mtb antigens.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

UM-1098 is a synthetic macrophage-Inducible C-type Lectin (Mincle) agonist, induces Th17, Th1, Th2 polarizing innate cytokines in mouse PBMCs, induces strong Th1 and Th17 immunity after vaccination with Mtb antigens.

Physicochemical Properties

M.Wt 1319.80
Formula C74H126O19
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

((2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-oxybis(3,4,5-trihydroxytetrahydro-2H-pyran-6,2-diyl))bis(methylene) bis(3,4,5-tris(octyloxy)benzoate)

References

1. Viktoria Rungelrath, et al. NPJ Vaccines. 2024 Jun 6;9(1):100.

2. Rungelrath V, et al. Vaccine X. 2025 Oct;26:100699.

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