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UNC1679

Chemical Structure : UNC1679

CAS No.: 1456885-62-3

UNC1679 (UNC-1679)

Catalog No.: PC-70161Not For Human Use, Lab Use Only.

UNC1679 is a potent and selective small molecule chemical probe of a methyl-lysine reader protein L3MBTL3 with Ki of 0.35 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    UNC1679 is a potent and selective small molecule chemical probe of a methyl-lysine reader protein L3MBTL3 with Ki of 0.35 uM.
    UNC1679 maintains in vitro and cellular potencyshows improved selectivity against other MBT-containing proteins compares with UNC1215.

    Physicochemical Properties

    M.Wt 446.595
    Formula C27H34N4O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(2-ethylisoindolin-5-yl)-4-(4-(pyrrolidin-2-yl)piperidine-1-carbonyl)benzamide

    References

    1. James LI, et al. J Med Chem. 2013 Sep 26;56(18):7358-71.

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