Chemical Structure : UNC4850
Catalog No.: PC-38275Not For Human Use, Lab Use Only.
UNC4850 (UNC-4850) is a specific small-molecule inhibitor toward CDY Chromodomain CDYL1/2 with Kd of 0.47/0.42 uM, >10-fold selectivity over CDY1, CBX5 and CBX7.
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UNC4850 (UNC-4850) is a specific small-molecule inhibitor toward CDY Chromodomain CDYL1/2 with Kd of 0.47/0.42 uM, >10-fold selectivity over CDY1, CBX5 and CBX7.
NC4850 is a close analog of UNC3866, UNC4850 binds to the chromodomain of CDYL1/2 about 10-fold more potently than to that of CBX7 by ITC.
M.Wt | 751.97 | |
Formula | C40H61N7O7 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Cheng Dong, et al. Cell Chem Biol. 2020 Jul 16;27(7):827-838.e7.
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