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UNC7437

Chemical Structure : UNC7437

CAS No.: 2967647-41-0

UNC7437 (UNC-7437)

Catalog No.: PC-25120Not For Human Use, Lab Use Only.

UNC7437 is a potent selective inhibitor of inositol phosphate multikinase (IPMK) with IC50 of 26.2 nM, decreased cellular proliferation and tritiated inositol phosphate levels in human U251-MG glioblastoma cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

UNC7437 is a potent selective inhibitor of inositol phosphate multikinase (IPMK) with IC50 of 26.2 nM, decreased cellular proliferation and tritiated inositol phosphate levels in human U251-MG glioblastoma cells.

Physicochemical Properties

M.Wt 293.32
Formula C18H15NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-3-(3-(3,5-Dimethylphenyl)benzo[c]isoxazol-5-yl)acrylic Acid

References

1. Zhou Y, et al. J Med Chem. 2025 Jul 25. doi: 10.1021/acs.jmedchem.5c00015.

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