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UR214-7

Chemical Structure : UR214-7

CAS No.: 2446433-32-3

UR214-7

Catalog No.: PC-27132Not For Human Use, Lab Use Only.

UR214-7 is a forchlorfenuron (FCF) analog and inhibitor of septin oligomeric assembly via preventing incorporation of SEPT2/7/9, into canonical hetero-octamers, decreases viability and proliferation in both ovarian and endometrial cancer cell lines, selectively suppress HER2 expression.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

UR214-7 is a forchlorfenuron (FCF) analog and inhibitor of septin oligomeric assembly via preventing incorporation of SEPT2/7/9, into canonical hetero-octamers, decreases viability and proliferation in both ovarian and endometrial cancer cell lines, selectively suppress HER2 expression.

Physicochemical Properties

M.Wt 333.67
Formula C13H8ClF4N3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(2-chloropyridin-4-yl)-3-(2-fluoro-3-(trifluoromethyl)phenyl)urea

References

1. Kim KK, et al. Sci Rep. 2020 Feb 24;10(1):3241.

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