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URB-597

Chemical Structure : URB-597

CAS No.: 546141-08-6

URB-597 (URB597;KDS-4103;URB 597;KDS 4103;KDS4103)

Catalog No.: PC-42720Not For Human Use, Lab Use Only.

URB-597 (KDS-4103) is a potent and selective FAAH inhibitor with IC50 of 4.6 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

URB-597 (KDS-4103) is a potent and selective FAAH inhibitor with IC50 of 4.6 nM.
URB-597 (KDS-4103) increases anandamide levels in the brain of rats and wild-type mice (0.3 mg/kg i.p.).
URB-597 (KDS-4103) improves cognitive impairment by inhibiting mTOR-dependent autophagy in a CCH model.

Physicochemical Properties

M.Wt 338.4003
Formula C20H22N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Carbamic acid, N-cyclohexyl-, 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester

References

1. Fegley D, et al. J Pharmacol Exp Ther. 2005 Apr;313(1):352-8.

2. Mor M, et al. J Med Chem. 2004 Oct 7;47(21):4998-5008.

3. Wang D, et al. Neuroscience. 2017 Mar 6;344:293-304.

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