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Chemical Structure : USL311
CAS No.: 1373268-67-7
Catalog No.: PC-73171Not For Human Use, Lab Use Only.
USL311 is a potent, selective, orally bioavailable CXCR4 antagonist, with potential antineoplastic activity.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $228 | In stock | |
| 25 mg | $398 | In stock | |
| 50 mg | $658 | In stock | |
| 100 mg | $988 | In stock | |
| 1 g | Get quote |
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USL311 is a potent, selective, orally bioavailable CXCR4 antagonist, with potential antineoplastic activity.
USL311 binds to CXCR4, prevente the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4 and inhibiting CXCR4 activation, decreases proliferation and migration of CXCR4-expressing tumor cells.
CXCR4, a chemokine receptor belonging to the G protein-coupled receptor (GPCR) family, plays an important role in chemotaxis and angiogenesis, and is upregulated in several tumor cell types.
| M.Wt | 422.577 | |
| Formula | C24H34N6O | |
| Appearance | Solid | |
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1. Peter Richardson. Usl-311 for use in the treatment of cancer. WO2018162924A1
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