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USP11 inhibitor 7

Chemical Structure : USP11 inhibitor 7

CAS No.:

USP11 inhibitor 7 (USP11-IN-2)

Catalog No.: PC-26235Not For Human Use, Lab Use Only.

USP11 inhibitor 7 (USP11-IN-2) is a selective inhibitor of USP11 with IC50 of 2.6 uM, shows >30- and 100-fold selective over USP4 and USP15.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

USP11 inhibitor 7 (USP11-IN-2) is a selective inhibitor of USP11 with IC50 of 2.6 uM, shows >30- and 100-fold selective over USP4 and USP15.
USP11 inhibitor 7 reduced the viability of platin-resistant ovarian cancer cells (PEO4) with IC50 of 2.0 uM.

Physicochemical Properties

M.Wt 373.88
Formula C20H24ClN3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(1-Benzylpiperidin-4-yl)-4-(2-chloroacetyl)-1-methyl-1H-pyrrole-2-carboxamide

References

1. Hassan MA, et al. ACS Omega. 2025 Dec 5;10(49):60555-60571.

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